Novel hydroxamates potentiated in vitro activity of fluconazole against Candida albicans

A set of 12 novel hydroxamate compounds (NHCs), structurally designed as inhibitors of histone deacetylase (HDAC) enzyme, were synthesized at our facility. These were adamantane derivatives with N-hydroxyacetamide as pharmacophore, and each of these compounds was tested for potentiating activity on...

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Pubblicato in:J Nat Sci Biol Med
Autori principali: Paul-Satyaseela, Maneesh, Hariharan, Periasamy, Bharani, Thirunavukkarasu, Franklyne, Jonathan S., Selvakumar, Thangapazham, Bharathimohan, Kuppusamy, Kumar, Chenniappan Vinoth, Kachhadia, Virendra, Narayanan, Shridhar, Rajagopal, Sridharan, Balasubramanian, Gopalan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Medknow Publications & Media Pvt Ltd 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320813/
https://ncbi.nlm.nih.gov/pubmed/28250687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0976-9668.198349
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