Novel hydroxamates potentiated in vitro activity of fluconazole against Candida albicans

A set of 12 novel hydroxamate compounds (NHCs), structurally designed as inhibitors of histone deacetylase (HDAC) enzyme, were synthesized at our facility. These were adamantane derivatives with N-hydroxyacetamide as pharmacophore, and each of these compounds was tested for potentiating activity on...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Nat Sci Biol Med
Hauptverfasser: Paul-Satyaseela, Maneesh, Hariharan, Periasamy, Bharani, Thirunavukkarasu, Franklyne, Jonathan S., Selvakumar, Thangapazham, Bharathimohan, Kuppusamy, Kumar, Chenniappan Vinoth, Kachhadia, Virendra, Narayanan, Shridhar, Rajagopal, Sridharan, Balasubramanian, Gopalan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Medknow Publications & Media Pvt Ltd 2017
Schlagworte:
Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320813/
https://ncbi.nlm.nih.gov/pubmed/28250687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0976-9668.198349
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge