Characterization of BRCA1 and BRCA2 variants in multi-ethnic Asian cohort from a Malaysian case-control study

BACKGROUND: Genetic testing for BRCA1 and BRCA2 has led to the accurate identification of individuals at higher risk of cancer and the development of new therapies. Approximately 10-20% of the genetic testing for BRCA1 and BRCA2 leads to the identification of variants of uncertain significance (VUS)...

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Bibliografski detalji
Izdano u:BMC Cancer
Glavni autori: Lai, Kah Nyin, Ho, Weang Kee, Kang, In Nee, Kang, Peter Choon Eng, Phuah, Sze Yee, Mariapun, Shivaani, Yip, Cheng-Har, Mohd Taib, Nur Aishah, Teo, Soo-Hwang
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320733/
https://ncbi.nlm.nih.gov/pubmed/28222693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3099-6
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