Nalaganje...
Construction, Characterization, and Complementation of a Conditional-Lethal DNA Topoisomerase IIα Mutant Human Cell Line
DNA Topoisomerase IIα (topoIIα) is a DNA decatenating enzyme, abundant constituent of mammalian mitotic chromosomes, and target of numerous antitumor drugs, but its exact role in chromosome structure and dynamics is unclear. In a powerful new approach to this important problem, with significant adva...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The American Society for Cell Biology
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC532048/ https://ncbi.nlm.nih.gov/pubmed/15456904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-08-0732 |
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