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Characterization of the TPX2 Domains Involved in Microtubule Nucleation and Spindle Assembly in Xenopus Egg Extracts

TPX2 has multiple functions during mitosis, including microtubule nucleation around the chromosomes and the targeting of Xklp2 and Aurora A to the spindle. We have performed a detailed domain functional analysis of TPX2 and found that a large N-terminal domain containing the Aurora A binding peptide...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Brunet, Stéphane, Sardon, Teresa, Zimmerman, Timo, Wittmann, Torsten, Pepperkok, Rainer, Karsenti, Eric, Vernos, Isabelle
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Cell Biology 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC532013/
https://ncbi.nlm.nih.gov/pubmed/15385625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-05-0385
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