Farnesoid X receptor (FXR) ablation sensitizes mice to hepatitis B virus X protein (HBx)-induced hepatocarcinogenesis

Chronic hepatitis B virus (HBV) infection is a major risk factor for hepatocellular carcinoma (HCC). Hepatitis B virus X protein (HBx) is a HBV protein that has multiple cellular functions, but its role in HCC pathogenesis has been controversial. The farnesoid X receptor (FXR) is a nuclear receptor...

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Udgivet i:Hepatology
Main Authors: Niu, Yongdong, Xu, Meishu, Slagle, Betty L., Huang, Haihua, Li, Song, Guo, Grace L., Shi, Ganggang, Qin, Wenxin, Xie, Wen
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319891/
https://ncbi.nlm.nih.gov/pubmed/28102638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28924
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