Molecular dissection of mutations at the heterozygous thymidine kinase locus in mouse lymphoma cells.

The mouse lymphoma L5178Y TK+/- 3.7.2C cell line allows quantitation of induced TK(+/-)----TK-/- mutations at the heterozygous thymidine kinase (Tk) locus. TK-/- mutant colonies show a bimodal size distribution, reflecting a difference in the growth rates of the two size classes that is hypothesized...

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Detalhes bibliográficos
Main Authors: Applegate, M L, Moore, M M, Broder, C B, Burrell, A, Juhn, G, Kasweck, K L, Lin, P F, Wadhams, A, Hozier, J C
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC53197/
https://ncbi.nlm.nih.gov/pubmed/1967496
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