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A system for assaying homologous recombination at the endogenous human thymidine kinase gene.

A system for assaying human interchromosomal recombination in vitro was developed, using a cell line containing two different mutant thymidine kinase genes (TK) on chromosomes 17. Heteroalleles were generated in the TK+/+ parent B-lymphoblast cell line WIL-2 by repeated exposure to the alkylating ni...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Benjamin, M B, Potter, H, Yandell, D W, Little, J B
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52146/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1677771/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.15.6652
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