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Interacting network of Hippo, Wnt/β-catenin and Notch signaling represses liver tumor formation
Acquiring a selective growth advantage by breaking the proliferation barrier established by gatekeeper genes is a centrally important event in tumor formation. Removal of the mammalian Hippo kinase Mst1 and Mst2 in hepatocytes leads to rapid hepatocellular carcinoma (HCC) formation, indicating that...
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| Publicado en: | BMB Rep |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Korean Society for Biochemistry and Molecular Biology
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5319656/ https://ncbi.nlm.nih.gov/pubmed/27881216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2017.50.1.196 |
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