Interacting network of Hippo, Wnt/β-catenin and Notch signaling represses liver tumor formation

Acquiring a selective growth advantage by breaking the proliferation barrier established by gatekeeper genes is a centrally important event in tumor formation. Removal of the mammalian Hippo kinase Mst1 and Mst2 in hepatocytes leads to rapid hepatocellular carcinoma (HCC) formation, indicating that...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:BMB Rep
Egile Nagusiak: Kim, Wantae, Khan, Sanjoy Kumar, Yang, Yingzi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Korean Society for Biochemistry and Molecular Biology 2017
Gaiak:
Perspective
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319656/
https://ncbi.nlm.nih.gov/pubmed/27881216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2017.50.1.196
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