Interacting network of Hippo, Wnt/β-catenin and Notch signaling represses liver tumor formation

Acquiring a selective growth advantage by breaking the proliferation barrier established by gatekeeper genes is a centrally important event in tumor formation. Removal of the mammalian Hippo kinase Mst1 and Mst2 in hepatocytes leads to rapid hepatocellular carcinoma (HCC) formation, indicating that...

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Bibliografiske detaljer
Udgivet i:BMB Rep
Main Authors: Kim, Wantae, Khan, Sanjoy Kumar, Yang, Yingzi
Format: Artigo
Sprog:Inglês
Udgivet: Korean Society for Biochemistry and Molecular Biology 2017
Fag:
Perspective
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319656/
https://ncbi.nlm.nih.gov/pubmed/27881216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2017.50.1.196
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