Melanoma antigen-specific effector T cell cytokine secretion patterns in patients treated with ipilimumab

BACKGROUND: In a previously reported study, patients with regionally advanced melanoma were treated with neoadjuvant ipilimumab (ipi) (Tarhini in PLoS ONE 9(2): e87705, 3). Significant changes in circulating myeloid derived suppressor cells (MDSC), regulatory T cells (Treg) and peptide specific type...

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Bibliographic Details
Published in:J Transl Med
Main Authors: Najjar, Yana G., Ding, Fei, Lin, Yan, VanderWeele, Robert, Butterfield, Lisa H., Tarhini, Ahmad A.
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319167/
https://ncbi.nlm.nih.gov/pubmed/28222797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1140-9
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