Phenotypic and functional testing of circulating regulatory T cells in advanced melanoma patients treated with neoadjuvant ipilimumab

BACKGROUND: We have previously investigated neoadjuvant ipilimumab (ipi) for patients with locally/regionally advanced melanoma. That initial assessment of peripheral blood mononuclear cells (PBMC) showed a significant increase in shared tumor associated antigen specific CD4(+) and CD8(+) T cell act...

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Bibliografske podrobnosti
izdano v:J Immunother Cancer
Main Authors: Retseck, Janet, VanderWeele, Robert, Lin, Hui-Min, Lin, Yan, Butterfield, Lisa H., Tarhini, Ahmad A.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915044/
https://ncbi.nlm.nih.gov/pubmed/27330811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-016-0141-1
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