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Mass Spectrometric Analysis of TRPM6 and TRPM7 Phosphorylation Reveals Regulatory Mechanisms of the Channel-Kinases

TRPM7 and TRPM6 were the first identified bifunctional channels to contain their own kinase domains, but how these channel-kinases are regulated is poorly understood. Previous studies identified numerous phosphorylation sites on TRPM7, but very little is known about TRPM6 phosphorylation or sites on...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cai, Na, Bai, Zhiyong, Nanda, Vikas, Runnels, Loren W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318989/
https://ncbi.nlm.nih.gov/pubmed/28220887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42739
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