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Nucleobindin 1 binds to multiple types of pre-fibrillar amyloid and inhibits fibrillization
During amyloid fibril formation, amyloidogenic polypeptides misfold and self assemble into soluble pre-fibrillar aggregates, i.e., protofibrils, which elongate and mature into insoluble fibrillar aggregates. An emerging class of chaperones, chaperone-like amyloid binding proteins (CLABPs), has been...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5318909/ https://ncbi.nlm.nih.gov/pubmed/28220836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42880 |
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