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Notch1-promoted TRPA1 expression in erythroleukemic cells suppresses erythroid but enhances megakaryocyte differentiation

The Notch1 pathway plays important roles in modulating erythroid and megakaryocyte differentiation. To screen the Notch1-related genes that regulate differentiation fate of K562 and HEL cells, the expression of transient receptor potential ankyrin 1 (TRPA1) was induced by Notch1 receptor intracellul...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Chen, Ji-Lin, Ping, Yueh-Hsin, Tseng, Min-Jen, Chang, Yuan-I, Lee, Hsin-Chen, Hsieh, Rong-Hong, Yeh, Tien-Shun
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318885/
https://ncbi.nlm.nih.gov/pubmed/28220825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42883
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