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The Activated Notch1 Receptor Cooperates with α-Enolase and MBP-1 in Modulating c-myc Activity
The Notch signal pathway plays multifaceted roles to promote or suppress tumorigenesis. The Notch1 receptor intracellular domain (N1IC), the activated form of the Notch1 receptor, activates the c-myc proto-oncogene. The complex of N1IC and transcription factor YY1 binds to the human c-myc promoter t...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2493368/ https://ncbi.nlm.nih.gov/pubmed/18490439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00175-08 |
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