Oxidized Low-Density Lipoprotein Immune Complex Priming of the Nlrp3 Inflammasome Involves TLR and FcγR Cooperation and Is Dependent on CARD9

Oxidized low-density lipoprotein (oxLDL) is known to activate inflammatory responses in a variety of cells, especially macrophages and dendritic cells. Interestingly, much of the oxLDL in circulation is complexed to Abs, and these resulting immune complexes (ICs) are a prominent feature of chronic i...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Rhoads, Jillian P., Lukens, John R., Wilhelm, Ashley J., Moore, Jared L., Mendez-Fernandez, Yanice, Kanneganti, Thirumala-Devi, Major, Amy S.
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2017
Assuntos:
Innate Immunity and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318843/
https://ncbi.nlm.nih.gov/pubmed/28130494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601563
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