AEG-1 is associated with hypoxia-induced hepatocellular carcinoma chemoresistance via regulating PI3K/AKT/HIF-1alpha/MDR-1 pathway

Hypoxia is a common characteristic of hepatocellular carcinoma (HCC) associated with reduced response to chemotherapy, thus increasing the probability of tumor recurrence. Astrocyte elevated gene-1 (AEG-1) has been involved in a wide array of cancer progression including proliferation, chemoresistan...

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Bibliografische gegevens
Gepubliceerd in:EXCLI J
Hoofdauteurs: Xie, Yong, Zhong, De-Wu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Leibniz Research Centre for Working Environment and Human Factors 2016
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318678/
https://ncbi.nlm.nih.gov/pubmed/28337106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2016-694
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