AEG-1 Contributes to Metastasis in Hypoxia-Related Ovarian Cancer by Modulating the HIF-1alpha/NF-kappaB/VEGF Pathway

OBJECTIVE: Ovarian carcinoma represents one of the deadliest malignancies among female cancer patients. Astrocyte-elevated gene-1 (AEG-1) participates in the ontogenesis of multiple human malignant diseases. Here we evaluated AEG-1, hypoxia-inducible factor- (HIF-) 1α, nuclear factor kappa-light-cha...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Yu, Xiaoyu, Wang, Yan, Qiu, Huilei, Song, Hongtao, Feng, Di, Jiang, Yang, Deng, Shuzhe, Meng, Hongxue, Geng, Jingshu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889902/
https://ncbi.nlm.nih.gov/pubmed/29770329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3145689
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