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Folic Acid Represses Hypoxia-Induced Inflammation in THP-1 Cells through Inhibition of the PI3K/Akt/HIF-1α Pathway

Though hypoxia has been implicated as a cause of inflammation, the underlying mechanism is not well understood. Folic acid has been shown to provide protection against oxidative stress and inflammation in patients with cardiovascular disease and various models approximating insult to tissue via infl...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Huang, Xiaoyan, He, Zhiying, Jiang, Xinwei, Hou, Mengjun, Tang, Zhihong, Zhen, Xiaozhou, Liang, Yuming, Ma, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4790958/
https://ncbi.nlm.nih.gov/pubmed/26974319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151553
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