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Transcriptional repression of hypoxia-inducible factor-1 (HIF-1) by the protein arginine methyltransferase PRMT1

Hypoxia-inducible factors (HIF-1 and HIF-2) are essential mediators for the adaptive transcriptional response of cells and tissues to low-oxygen conditions. Under hypoxia or when cells are treated with various nonhypoxic stimuli, the active HIF-α subunits are mainly regulated through increased prote...

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Détails bibliographiques
Auteurs principaux: Lafleur, Véronique N., Richard, Stéphane, Richard, Darren E.
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952860/
https://ncbi.nlm.nih.gov/pubmed/24451260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-07-0423
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