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Protein arginine methyltransferase 1 (PRMT1) represses MHC II transcription in macrophages by methylating CIITA
Efficient presentation of alien antigens triggers activation of T lymphocytes and robust host defense against invading pathogens. This pathophysiological process relies on the expression of major histocompatibility complex (MHC) molecules in antigen presenting cells such as macrophages. Aberrant MHC...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5240148/ https://ncbi.nlm.nih.gov/pubmed/28094290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40531 |
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