CBP/p300 acetyltransferases regulate the expression of NKG2D ligands on tumor cells

Tumor surveillance of natural killer (NK) cells is mediated by the cytotoxicity receptor natural-killer group 2 member D (NKG2D). Ligands for NKG2D are generally not expressed on healthy cells, but induced on the surface of malignant cells. To date, NKG2D ligand (NKG2D-L) induction was mainly descri...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncogene
Auteurs principaux: Sauer, M, Schuldner, M, Hoffmann, N, Cetintas, A, Reiners, K S, Shatnyeva, O, Hallek, M, Hansen, H P, Gasser, S, von Strandmann, E P
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318661/
https://ncbi.nlm.nih.gov/pubmed/27477692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.259
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