Lack of ABCG2 Leads to Biventricular Dysfunction and Remodeling in Response to Hypoxia

Aims: The ATP-binding cassette (ABC)G2 transporter protects the heart from pressure overload-induced ventricular dysfunction but also protects cancer cells from chemotherapeutic agents. It is upregulated in the myocardium of heart failure patients and clears hypoxia-induced intracellular metabolites...

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Vydáno v:Front Physiol
Hlavní autoři: Nagy, Bence M., Nagaraj, Chandran, Egemnazarov, Bakytbek, Kwapiszewska, Grazyna, Stauber, Rudolf E., Avian, Alexander, Olschewski, Horst, Olschewski, Andrea
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318436/
https://ncbi.nlm.nih.gov/pubmed/28270772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00098
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