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Lack of ABCG2 Leads to Biventricular Dysfunction and Remodeling in Response to Hypoxia
Aims: The ATP-binding cassette (ABC)G2 transporter protects the heart from pressure overload-induced ventricular dysfunction but also protects cancer cells from chemotherapeutic agents. It is upregulated in the myocardium of heart failure patients and clears hypoxia-induced intracellular metabolites...
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| Опубликовано в: : | Front Physiol |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Frontiers Media S.A.
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5318436/ https://ncbi.nlm.nih.gov/pubmed/28270772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00098 |
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