Protein cysteine oxidation in redox signaling: caveats on sulfenic acid detection and quantification

Oxidation of critical signaling protein cysteines regulated by H(2)O(2) has been considered to involve sulfenic acid (RSOH) formation. RSOH may subsequently form either a sulfenyl amide (RSNHR’) with a neighboring amide, or a mixed disulfide (RSSR’) with another protein cysteine or glutathione. Prev...

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Detalhes bibliográficos
Publicado no:Arch Biochem Biophys
Main Authors: Forman, Henry Jay, Davies, Michael J., Krämer, Anna C., Miotto, Giovanni, Zaccarin, Mattia, Zhang, Hongqiao, Ursini, Fulvio
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318241/
https://ncbi.nlm.nih.gov/pubmed/27693037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2016.09.013
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