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Signaling by 4-hydroxy-2-nonenal: exposure protocols, target selectivity and degradation

4-hydroxy-2-nonenal (HNE), a major non-saturated aldehyde product of lipid peroxidation, has been extensively studied as a signaling messenger. In these studies a wide range of HNE concentrations have been used, ranging from the unstressed plasma concentration to far beyond what would be found in ac...

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Foilsithe in:Arch Biochem Biophys
Main Authors: Zhang, Hongqiao, Forman, Henry Jay
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318232/
https://ncbi.nlm.nih.gov/pubmed/27840096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2016.11.003
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