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Design, synthesis and evaluation of anti-CD123 antibody drug conjugates
Leukemia stem cells (LSCs) account for the development of drug resistance and increased recurrence rate in acute myeloid leukemia (AML) patients. Targeted drug delivery to leukemia stem cells remains a major challenge in AML chemotherapy. Overexpressed interleukin-3 receptor alpha chain, CD123, on t...
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| Publicado no: | Bioorg Med Chem |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5318162/ https://ncbi.nlm.nih.gov/pubmed/27687970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2016.09.043 |
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