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Cationic liposomes promote antigen cross-presentation in dendritic cells by alkalizing the lysosomal pH and limiting the degradation of antigens

Cationic liposomes (CLs) have been widely examined as vaccine delivery nanoparticles since they can form complexes with biomacromolecules, promote delivery of antigens and adjuvant molecules to antigen-presenting cells (APCs), and mediate cellular uptake of vaccine components. CLs are also known to...

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Bibliografiske detaljer
Udgivet i:Int J Nanomedicine
Main Authors: Gao, Jie, Ochyl, Lukasz J, Yang, Ellen, Moon, James J
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5317250/
https://ncbi.nlm.nih.gov/pubmed/28243087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S125866
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