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Cationic liposomes promote antigen cross-presentation in dendritic cells by alkalizing the lysosomal pH and limiting the degradation of antigens

Cationic liposomes (CLs) have been widely examined as vaccine delivery nanoparticles since they can form complexes with biomacromolecules, promote delivery of antigens and adjuvant molecules to antigen-presenting cells (APCs), and mediate cellular uptake of vaccine components. CLs are also known to...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Gao, Jie, Ochyl, Lukasz J, Yang, Ellen, Moon, James J
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5317250/
https://ncbi.nlm.nih.gov/pubmed/28243087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S125866
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