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Targeted concurrent and sequential delivery of chemotherapeutic and antiangiogenic agents to the brain by using drug-loaded nanofibrous membranes

Glioblastoma is the most frequent and devastating primary brain tumor. Surgery followed by radiotherapy with concomitant and adjuvant chemotherapy is the standard of care for patients with glioblastoma. Chemotherapy is ineffective, because of the low therapeutic levels of pharmaceuticals in tumor ti...

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Enregistré dans:
Détails bibliographiques
Publié dans:Int J Nanomedicine
Auteurs principaux: Tseng, Yuan-Yun, Yang, Tao-Chieh, Wang, Yi-Chuan, Lee, Wei-Hwa, Chang, Tzu-Min, Kau, Yi-Chuan, Liu, Shih-Jung
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5317248/
https://ncbi.nlm.nih.gov/pubmed/28243088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S124593
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