Advanced interstitial chemotherapy combined with targeted treatment of malignant glioma in rats by using drug-loaded nanofibrous membranes

Glioblastoma multiforme (GBM), the most prevalent and malignant form of a primary brain tumour, is resistant to chemotherapy. In this study, we concurrently loaded three chemotherapeutic agents [bis-chloroethylnitrosourea, irinotecan, and cisplatin; BIC] into 50:50 poly[(d,l)-lactide-co-glycolide] (...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tseng, Yuan-Yun, Su, Chen-Hsing, Yang, Shun-Tai, Huang, Yin-Chen, Lee, Wei-Hwa, Wang, Yi-Chuan, Liu, Shou-Cheng, Liu, Shih-Jung
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312357/
https://ncbi.nlm.nih.gov/pubmed/27494894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10989
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