Targeted concurrent and sequential delivery of chemotherapeutic and antiangiogenic agents to the brain by using drug-loaded nanofibrous membranes

Glioblastoma is the most frequent and devastating primary brain tumor. Surgery followed by radiotherapy with concomitant and adjuvant chemotherapy is the standard of care for patients with glioblastoma. Chemotherapy is ineffective, because of the low therapeutic levels of pharmaceuticals in tumor ti...

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Bibliographic Details
Published in:Int J Nanomedicine
Main Authors: Tseng, Yuan-Yun, Yang, Tao-Chieh, Wang, Yi-Chuan, Lee, Wei-Hwa, Chang, Tzu-Min, Kau, Yi-Chuan, Liu, Shih-Jung
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2017
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5317248/
https://ncbi.nlm.nih.gov/pubmed/28243088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S124593
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