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Three pairs of Weak interactions precisely regulate the G-loop gate of Kir2.1 Channel
Kir2.1 (also known as IRK1) plays key roles in the regulation of resting membrane potential and cell excitability. To achieve its physiological roles, Kir2.1 performs a series of conformational transitions, named as gating. However, the structural basis of gating is still obscure. Here, we combined...
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| Pubblicato in: | Proteins |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5317092/ https://ncbi.nlm.nih.gov/pubmed/27699887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25176 |
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