The non-coding variant rs1800734 enhances DCLK3 expression through long-range interaction and promotes colorectal cancer progression

Genome-wide association studies have identified a great number of non-coding risk variants for colorectal cancer (CRC). To date, the majority of these variants have not been functionally studied. Identification of allele-specific transcription factor (TF) binding is of great importance to understand...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nat Commun
मुख्य लेखकों: Liu, Ning Qing, ter Huurne, Menno, Nguyen, Luan N., Peng, Tianran, Wang, Shuang-Yin, Studd, James B., Joshi, Onkar, Ongen, Halit, Bramsen, Jesper B, Yan, Jian, Andersen, Claus L., Taipale, Jussi, Dermitzakis, Emmanouil T., Houlston, Richard S., Hubner, Nina C., Stunnenberg, Hendrik G.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2017
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316867/
https://ncbi.nlm.nih.gov/pubmed/28195176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14418
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