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Critical Role for P53 in Regulating the Cell Cycle of Ground State Embryonic Stem Cells
Mouse embryonic stem cells (ESCs) grown in serum-supplemented conditions are characterized by an extremely short G1 phase due to the lack of G1-phase control. Concordantly, the G1-phase-specific P53-P21 pathway is compromised in serum ESCs. Here, we provide evidence that P53 is activated upon transi...
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| Publicado no: | Stem Cell Reports |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7013234/ https://ncbi.nlm.nih.gov/pubmed/32004494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.01.001 |
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