TLR7 Deficiency Leads to TLR8 Compensative Regulation of Immune Response against JEV in Mice

Japanese encephalitis virus (JEV) is a highly fatal pathogen to human beings. Toll-like receptor 7 (TLR7) plays a role as the first host defense against most single-stranded RNA flaviviruses. This study aims to investigate the role of TLR7 in inducing adaptive immune response in mice against JEV. In...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Awais, Muhammad, Wang, Ke, Lin, Xianwu, Qian, Wenjie, Zhang, Nan, Wang, Chong, Wang, Kunlun, Zhao, Ling, Fu, Zhen F., Cui, Min
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316529/
https://ncbi.nlm.nih.gov/pubmed/28265274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00160
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