TLR8 deficiency leads to autoimmunity in mice

TLRs play an essential role in the induction of immune responses by detecting conserved molecular products of microorganisms. However, the function of TLR8 is largely unknown. In the current study, we investigated the role of TLR8 signaling in immunity in mice. We found that Tlr8(–/–) DCs overexpres...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Demaria, Olivier, Pagni, Philippe P., Traub, Stephanie, de Gassart, Aude, Branzk, Nora, Murphy, Andrew J., Valenzuela, David M., Yancopoulos, George D., Flavell, Richard A., Alexopoulou, Lena
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947223/
https://ncbi.nlm.nih.gov/pubmed/20811154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42081
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados