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Regulation of membrane type-1 matrix metalloproteinase activity and intracellular localization in clinical thoracic aortic aneurysms
OBJECTIVE: Membrane type-1 MMP (MT1-MMP) is elevated during thoracic aortic aneurysm (TAA) development in mouse models, and plays an important role in the activation of MMP-2 and the release of matrix bound TGF-β. This study tested the hypothesis that MT1-MMP is subject to protein kinase C (PKC)-med...
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| 出版年: | J Thorac Cardiovasc Surg |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5316335/ https://ncbi.nlm.nih.gov/pubmed/27923483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2016.10.065 |
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