Potentiation of the NO-cGMP pathway and blood flow responses during dynamic exercise in healthy humans

PURPOSE: Previous work has shown nitric oxide (NO) contributes to ~15% of the hyperemic response to dynamic exercise in healthy humans. This NO-mediated vasodilation occurs, in part, via increases in intracellular cyclic guanosine monophosphate (cGMP), which is catabolized by phosphodiesterase. We s...

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Publicat a:Eur J Appl Physiol
Autors principals: Limberg, Jacqueline K., Malterer, Katherine R., Kellawan, J. Mikhail, Schrage, William G., Wilkins, Brad W., Nicholson, Wayne T., Eisenach, John H., Joyner, Michael J., Curry, Timothy B.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5315588/
https://ncbi.nlm.nih.gov/pubmed/28013386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00421-016-3523-7
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