Brain-derived neurotrophic factor protects against tau-related neurodegeneration of Alzheimer's disease

Reduced expression of brain-derived neurotrophic factor (BDNF) has a crucial role in the pathogenesis of Alzheimer's disease (AD), which is characterized with the formation of neuritic plaques consisting of amyloid-beta (Aβ) and neurofibrillary tangles composed of hyperphosphorylated tau protei...

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Publicat a:Transl Psychiatry
Autors principals: Jiao, S-S, Shen, L-L, Zhu, C, Bu, X-L, Liu, Y-H, Liu, C-H, Yao, X-Q, Zhang, L-L, Zhou, H-D, Walker, D G, Tan, J, Götz, J, Zhou, X-F, Wang, Y-J
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5315549/
https://ncbi.nlm.nih.gov/pubmed/27701410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2016.186
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