Local and distant relationships between amyloid, tau and neurodegeneration in Alzheimer's Disease

The relationships between β-amyloid (Aβ), tau and neurodegeneration within Alzheimer's Disease pathogenesis are not fully understood. To explore these associations in vivo, we evaluated 30 Aβ PET-positive patients (mean ± sd age 62.4 ± 8.3) with mild probable AD and 12 Aβ PET-negative healthy c...

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Publicado en:Neuroimage Clin
Autores principales: Iaccarino, Leonardo, Tammewar, Gautam, Ayakta, Nagehan, Baker, Suzanne L., Bejanin, Alexandre, Boxer, Adam L., Gorno-Tempini, Maria Luisa, Janabi, Mustafa, Kramer, Joel H., Lazaris, Andreas, Lockhart, Samuel N., Miller, Bruce L., Miller, Zachary A., O'Neil, James P., Ossenkoppele, Rik, Rosen, Howard J., Schonhaut, Daniel R., Jagust, William J., Rabinovici, Gil D.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2017
Materias:
Regular Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5684433/
https://ncbi.nlm.nih.gov/pubmed/29159058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2017.09.016
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