The p53 isoform delta133p53ß regulates cancer cell apoptosis in a RhoB-dependent manner

The TP53 gene plays essential roles in cancer. Conventionally, wild type (WT) p53 is thought to prevent cancer development and metastasis formation, while mutant p53 has transforming abilities. However, clinical studies failed to establish p53 mutation status as an unequivocal predictive or prognost...

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Udgivet i:PLoS One
Main Authors: Arsic, Nikola, Ho-Pun-Cheung, Alexandre, Evelyne, Crapez, Assenat, Eric, Jarlier, Marta, Anguille, Christelle, Colard, Manon, Pezet, Mikaël, Roux, Pierre, Gadea, Gilles
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5315499/
https://ncbi.nlm.nih.gov/pubmed/28212429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172125
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