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The p53 Isoform Δ133p53β Promotes Cancer Stem Cell Potential
Cancer stem cells (CSC) are responsible for cancer chemoresistance and metastasis formation. Here we report that Δ133p53β, a TP53 splice variant, enhanced cancer cell stemness in MCF-7 breast cancer cells, while its depletion reduced it. Δ133p53β stimulated the expression of the key pluripotency fac...
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| 出版年: | Stem Cell Reports |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4400643/ https://ncbi.nlm.nih.gov/pubmed/25754205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.02.001 |
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