A Single Course of Anti-CD3 Monoclonal Antibody hOKT3γ1(Ala-Ala) Results in Improvement in C-Peptide Responses and Clinical Parameters for at Least 2 Years after Onset of Type 1 Diabetes

Despite advances in understanding autoimmune diabetes in animal models, there has been little progress in altering the natural course of the human disease, which involves progression to insulin deficiency. Studies with immunosuppressive agents have shown short-term effectiveness, but they have not i...

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Veröffentlicht in:Diabetes
Hauptverfasser: Herold, Kevan C., Gitelman, Stephen E., Masharani, Umesh, Hagopian, William, Bisikirska, Brygida, Donaldson, David, Rother, Kristina, Diamond, Beverly, Harlan, David M., Bluestone, Jeffrey A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2005
Schlagworte:
Immunology and Transplantation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5315015/
https://ncbi.nlm.nih.gov/pubmed/15919798
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