Učitavanje...
TCR stimulation with modified anti-CD3 mAb expands CD8(+) T cell population and induces CD8(+)CD25(+) Tregs
Modified anti-CD3 mAbs are emerging as a possible means of inducing immunologic tolerance in settings including transplantation and autoimmunity such as in type 1 diabetes. In a trial of a modified anti-CD3 mAb [hOKT3γ1(Ala-Ala)] in patients with type 1 diabetes, we identified clinical responders by...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
2005
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1201661/ https://ncbi.nlm.nih.gov/pubmed/16167085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI23961 |
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