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Stem cell-based treatment of Pelizaeus Merzbacher disease

Pelizaeus-Merzbacher disease (PMD) is an X-linked disorder caused by mutation in the PLP1 gene, which encodes the proteolipid protein of myelinating oligodendroglia. PMD exhibits phenotypic variability that reflects its considerable genotypic heterogeneity, but all forms of the disease result in cen...

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Détails bibliographiques
Publié dans:Stem Cells
Auteurs principaux: Osorio, M. Joana, Rowitch, David H., Tesar, Paul, Wernig, Marius, Windrem, Martha S., Goldman, Steven A.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314962/
https://ncbi.nlm.nih.gov/pubmed/27882623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2530
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