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Stem cell-based treatment of Pelizaeus Merzbacher disease

Pelizaeus-Merzbacher disease (PMD) is an X-linked disorder caused by mutation in the PLP1 gene, which encodes the proteolipid protein of myelinating oligodendroglia. PMD exhibits phenotypic variability that reflects its considerable genotypic heterogeneity, but all forms of the disease result in cen...

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Dades bibliogràfiques
Publicat a:Stem Cells
Autors principals: Osorio, M. Joana, Rowitch, David H., Tesar, Paul, Wernig, Marius, Windrem, Martha S., Goldman, Steven A.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314962/
https://ncbi.nlm.nih.gov/pubmed/27882623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2530
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