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Stem cell-based treatment of Pelizaeus Merzbacher disease

Pelizaeus-Merzbacher disease (PMD) is an X-linked disorder caused by mutation in the PLP1 gene, which encodes the proteolipid protein of myelinating oligodendroglia. PMD exhibits phenotypic variability that reflects its considerable genotypic heterogeneity, but all forms of the disease result in cen...

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Bibliografiske detaljer
Udgivet i:Stem Cells
Main Authors: Osorio, M. Joana, Rowitch, David H., Tesar, Paul, Wernig, Marius, Windrem, Martha S., Goldman, Steven A.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314962/
https://ncbi.nlm.nih.gov/pubmed/27882623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2530
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