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Stem cell-based treatment of Pelizaeus Merzbacher disease

Pelizaeus-Merzbacher disease (PMD) is an X-linked disorder caused by mutation in the PLP1 gene, which encodes the proteolipid protein of myelinating oligodendroglia. PMD exhibits phenotypic variability that reflects its considerable genotypic heterogeneity, but all forms of the disease result in cen...

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Bibliografski detalji
Izdano u:Stem Cells
Glavni autori: Osorio, M. Joana, Rowitch, David H., Tesar, Paul, Wernig, Marius, Windrem, Martha S., Goldman, Steven A.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314962/
https://ncbi.nlm.nih.gov/pubmed/27882623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2530
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