EBI2 overexpression in mice leads to B1 B-cell expansion and chronic lymphocytic leukemia–like B-cell malignancies

Human and mouse chronic lymphocytic leukemia (CLL) develops from CD5(+) B cells that in mice and macaques are known to define the distinct B1a B-cell lineage. B1a cells are characterized by lack of germinal center (GC) development, and the B1a cell population is increased in mice with reduced GC for...

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Bibliografski detalji
Izdano u:Blood
Glavni autori: Niss Arfelt, Kristine, Barington, Line, Benned-Jensen, Tau, Kubale, Valentina, Kovalchuk, Alexander L., Daugvilaite, Viktorija, Christensen, Jan Pravsgaard, Thomsen, Allan Randrup, Egerod, Kristoffer L., Bassi, Maria R., Spiess, Katja, Schwartz, Thue W., Wang, Hongsheng, Morse, Herbert C., Holst, Peter J., Rosenkilde, Mette M.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2017
Teme:
Lymphoid Neoplasia
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314812/
https://ncbi.nlm.nih.gov/pubmed/28003273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-02-697185
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